Inoue R, Hosomi K, Park J, Sakaue H, Yumioka H, Kamitani H, Kinugasa Y, Harano K, Syauki AY, Doi M, Kageyama S, Yamamoto K, Mizuguchi K, Kunisawa J, Irie Y (2024) Clinical phenotypes associated with the gut microbiome in older Japanese people with care needs in a nursing home. Nutrients 16(22):3839. PMID: 39599625. doi: 10.3390/nu16223839.
Maruyama S, Matsuoka T, Hosomi K, Park J, Murakami H, Miyachi M, Kawashima H, Mizuguchi K, Kobayashi T, Ooka T, Yamagata Z, Kunisawa J (2024) High barley intake in non-obese individuals is associated with high natto consumption and abundance of butyrate-producing bacteria in the gut: a cross-sectional study. Front Nutr 11:1434150. PMID: 39545049. doi: 10.3389/fnut.2024.1434150.
Kageyama S, Inoue R, Hosomi K, Park J, Yumioka H, Doi M, Miyake M, Nagashio Y, Shibuya Y, Oka N, Akazawa H, Kanzaki S, Mizuguchi K, Kunisawa J, Irie Y (2024) Association between gut microbiome composition and physical characteristics in patients with severe motor and intellectual disabilities: perspectives from microbial diversity. Nutrients 16(20):3546. PMID: 39458540. doi: 10.3390/nu16203546.
Sono M, Iimori K, Nagao M, Ogawa S, Maruno T, Nakanishi Y, Anazawa T, Nagai K, Masui T, Mori H, Hosomi K, Kunisawa J, Yokota H, Tanaka Y, Ohno H, Hatano E, Fukuda A, Seno H (2024) Reduction of butyrate-producing bacteria in the gut microbiome of Japanese patients with pancreatic cancer. Pancreatology 24(7):1031-1039. PMID: 39256134. doi: 10.1016/j.pan.2024.09.002.
Uchida M, Park J, Fujie S, Hosomi K, Horii N, Watanabe K, Sanada K, Shinohara Y, Mizuguchi K, Kunisawa J, Iemitsu M, Miyachi M (2024) Effect of resistance training and chicken meat on muscle strength and mass and the gut microbiome of older women: a randomized controlled trial. Physiol Rep 12(12):e16100. PMID: 38888088. doi: 10.14814/phy2.16100.
Toda K, Yoshimoto S, Yoshida K, Mitsuyama E, Iwabuchi N, Hosomi K, Sanada TJ, Tanaka M, Nanri H, Kunisawa J, Odamaki T, Miyachi M (2024) An exploratory study on seasonal variation in the gut microbiota of athletes: insights from Japanese handball players. Microorganisms 12(4):781. PMID: 38674725. doi: 10.3390/microorganisms12040781.
Iwasaka C, Nanri H, Nakagata T, Ohno H, Tanisawa K, Konishi K, Murakami H, Hosomi K, Park J, Yamada Y, Ono R, Mizuguchi K, Kunisawa J, Miyachi M (2024) Association of skeletal muscle function, quantity, and quality with gut microbiota in Japanese adults: a cross-sectional study. Geriatr Gerontol Int 24(1):53-60. PMID: 38098315. doi: 10.1111/ggi.14751.
Yoshimura E, Hamada Y, Hatamoto Y, Nakagata T, Nanri H, Nakayama Y, Hayashi T, Suzuki I, Ando T, Ishikawa-Takata K, Tanaka S, Ono R, Park J, Hosomi K, Mizuguchi K, Kunisawa J, Miyachi M (2024) Effects of energy loads on energy and nutrient absorption rates and gut microbiome in humans: a randomized crossover trial. Obesity (Silver Spring) 32(2):262-272. PMID: 37927202. doi: 10.1002/oby.23935.
Kageyama S, Inoue R, Park J, Hosomi K, Yumioka H, Suka T, Teramoto K, Syauki AY, Doi M, Sakaue H, Miyake M, Mizuguchi K, Kunisawa J, Irie Y (2023) Changes in fecal gut microbiome of home healthcare patients with disabilities through consumption of malted rice amazake. Physiol Genomics 55(12):647-653. PMID: 37694281. doi: 10.1152/physiolgenomics.00062.2023.
Park J, Bushita H, Nakano A, Hara A, Ueno HM, Ozato N, Hosomi K, Kawashima H, Chen YA, Mohsen A, Ohno H, Konishi K, Tanisawa K, Nanri H, Murakami H, Miyachi M, Kunisawa J, Mizuguchi K, Araki M (2023) Ramen consumption and gut microbiota diversity in Japanese women: cross-sectional data from the NEXIS cohort study. Microorganisms 11(8):1892. PMID: 37630452. doi: 10.3390/microorganisms11081892.
Akazawa N, Nakamura M, Eda N, Murakami H, Nakagata T, Nanri H, Park J, Hosomi K, Mizuguchi K, Kunisawa J, Miyachi M, Hoshikawa M (2023) Gut microbiota alternation with training periodization and physical fitness in Japanese elite athletes. Front Sports Act Living 5: 1219345. PMID: 37521099. doi: 10.3389/fspor.2023.1219345.
Maruyama S, Matsuoka T, Hosomi K, Park J, Nishimura M, Murakami H, Konishi K, Miyachi M, Kawashima H, Mizuguchi K, Kobayashi T, Ooka T, Yamagata Z, Kunisawa J (2023) Characteristic gut bacteria in high barley consuming Japanese individuals without hypertension. Microorganisms 11(5): 1246. PMID: 37317220. doi: 10.3390/microorganisms11051246.
Sawane K, Hosomi K, Park J, Ookoshi K, Nanri H, Nakagata T, Chen YA, Mohsen A, Kawashima H, Mizuguchi K, Miyachi M, Kunisawa J (2022) Identification of human gut microbiome associated with enterolignan production. Microorganisms 10(11): 2169. PMID: 36363762. doi: 10.3390/microorganisms10112169.
Mohsen A, Chen YA, Osorio RSA, Higuchi C, Mizuguchi K (2022) Snaq: a dynamic snakemake pipeline for microbiome data analysis with QIIME2. Front Bioinform 2: 893933. PMID: 36304319. doi: 10.3389/fbinf.2022.893933.
Hosomi K, Saito M, Park J, Murakami H, Shibata N, Ando M, Nagatake T, Konishi K, Ohno H, Tanisawa K, Mohsen A, Chen YA, Kawashima H, Natsume-Kitatani Y, Oka Y, Shimizu H, Furuta M, Tojima Y, Sawane K, Saika A, Yonejima Y, Takeyama H, Matsutani A, Mizuguchi K, Miyachi M, Kunisawa J (2022) Oral administration of Blautia wexlerae ameliorates obesity and type 2 diabetes via metabolic remodeling of the gut microbiota. Nat Commun 13(1): 4477. PMID: 35982037. doi: 10.1038/s41467-022-32015-7.
Park J, Hosomi K, Kawashima H, Chen YA, Mohsen A, Ohno H, Konishi K, Tanisawa K, Kifushi M, Kogawa M, Takeyama H, Murakami H, Kubota T, Miyachi M, Kunisawa J, Mizuguchi K (2022) Dietary vitamin B1 intake influences gut microbial community and the consequent production of short-chain fatty acids. Nutrients 14(10): 2078. PMID: 35631219. doi: 10.3390/nu14102078.
Maruyama S, Matsuoka T, Hosomi K, Park J, Nishimura M, Murakami H, Konishi K, Miyachi M, Kawashima H, Mizuguchi K, Kobayashi T, Ooka T, Yamagata Z, Kunisawa J (2022) Classification of the occurrence of dyslipidemia based on gut bacteria related to barley intake. Front Nutr 9: 812469. PMID: 35399681. doi: 10.3389/fnut.2022.812469.
Ikubo Y, Sanada TJ, Hosomi K, Park J, Naito A, Shoji H, Misawa T, Suda R, Sekine A, Sugiura T, Shigeta A, Nanri H, Sakao S, Tanabe N, Mizuguchi K, Kunisawa J, Suzuki T, Tatsumi K (2022) Altered gut microbiota and its association with inflammation in patients with chronic thromboembolic pulmonary hypertension: a single-center observational study in Japan. BMC Pulm Med 22(1):138. PMID: 35395844. doi: 10.1186/s12890-022-01932-0.
Matsuoka T, Hosomi K, Park J, Goto Y, Nishimura M, Maruyama S, Murakami H, Konishi K, Miyachi M, Kawashima H, Mizuguchi K, Kobayashi T, Yokomichi H, Kunisawa J, Yamagata Z (2022) Relationships between barley consumption and gut microbiome characteristics in a healthy Japanese population: a cross-sectional study. BMC Nutr 8(1): 23. PMID: 35287729. doi: 10.1186/s40795-022-00500-3.
Tourlousse DM, Narita K, Miura T, Ohashi A, Matsuda M, Ohyama Y, Shimamura M, Furukawa M, Kasahara K, Kameyama K, Saito S, Goto M, Shimizu R, Mishima R, Nakayama J, Hosomi K, Kunisawa J, Terauchi J, Sekiguchi Y, Kawasaki H (2022) Characterization and demonstration of mock communities as control reagents for accurate human microbiome community measurements. Microbiol Spectr 10(2):e0191521. PMID: 35234490. doi: 10.1128/spectrum.01915-21.
Otoshi T, Nagano T, Park J, Hosomi K, Yamashita T, Tachihara M, Tabata T, Sekiya R, Tanaka Y, Kobayashi K, Mizuguchi K, Itoh T, Maniwa Y, Kunisawa J, Nishimura Y (2022) The gut microbiome as a biomarker of cancer progression among female never-smokers with lung adenocarcinoma. Anticancer Res 42(3): 1589-1598. PMID: 35220256 doi: 10.21873/anticanres.15633.
Miki Y, Taketomi Y, Kidoguchi Y, Yamamoto K, Muramatsu K, Nishito Y, Park J, Hosomi K, Mizuguchi K, Kunisawa J, Soga T, Boilard E, B Gowda SG, Ikeda K, Arita M, Murakami M (2022) Group IIA secreted phospholipase A2 controls skin carcinogenesis and psoriasis by shaping the gut microbiota. JCI Insight 7(2): e152611. PMID: 35076024. doi: 10.1172/jci.insight.152611.
Nagatake T, Kishino S, Urano E, Murakami H, Kitamura N, Konishi K, Ohno H, Tiwari P, Morimoto S, Node E, Adachi J, Abe Y, Isoyama J, Sawane K, Honda T, Inoue A, Uwamizu A, Matsuzaka T, Miyamoto Y, Hirata SI, Saika A, Shibata Y, Hosomi K, Matsunaga A, Shimano H, Arita M, Aoki J, Oka M, Matsutani A, Tomonaga T, Kabashima K, Miyachi M, Yasutomi Y, Ogawa J, Kunisawa J (2022) Intestinal microbe-dependent ω3 lipid metabolite αKetoA prevents inflammatory diseases in mice and cynomolgus macaques. Mucosal Immunol 15(2): 289-300. PMID: 35013573. doi: 10.1038/s41385-021-00477-5.
Kageyama S, Inoue R, Hosomi K, Park J, Yumioka H, Suka T, Kurohashi Y, Teramoto K, Syauki AY, Doi M, Sakaue H, Mizuguchi K, Kunisawa J, Irie Y (2021) Effects of malted rice amazake on constipation symptoms and gut microbiota in children and adults with severe motor and intellectual disabilities: a pilot study. Nutrients 13(12): 4466. PMID: 34960021. doi: 10.3390/nu13124466.
Ueta M, Hosomi K, Park J, Mizuguchi K, Sotozono C, Kinoshita S, Kunisawa J (2021) Categorization of the ocular microbiome in Japanese Stevens-Johnson syndrome patients with severe ocular complications. Front Cell Infect Microbiol 11: 741654. PMID: 34869055. doi: 10.3389/fcimb.2021.741654.
Tsunematsu Y, Hosomi K, Kunisawa J, Sato M, Shibuya N, Saito E, Murakami H, Yoshikawa Y, Iwashita Y, Miyoshi N, Mutoh M, Ishikawa H, Sugimura H, Miyachi M, Wakabayashi K, Watanabe K (2021) Mother-to-infant transmission of the carcinogenic colibactin-producing bacteria. BMC Microbiol 21(1):235. PMID: 34429063. doi: 10.1186/s12866-021-02292-1.
Watanabe D, Murakami H, Ohno H, Tanisawa K, Konishi K, Todoroki-Mori K, Tsunematsu Y, Sato M, Ogata Y, Miyoshi N, Kubota N, Kunisawa J, Wakabayashi K, Kubota T, Watanabe K, Miyachi M (2021) Stool pattern is associated with not only the prevalence of tumorigenic bacteria isolated from fecal matter but also plasma and fecal fatty acids in healthy Japanese adults. BMC Microbiol 21(1): 196. PMID: 34182940. doi: 10.1186/s12866-021-02255-6.
Park J, Kato K, Murakami H, Hosomi K, Tanisawa K, Nakagata T, Ohno H, Konishi K, Kawashima H, Chen YA, Mohsen A, Xiao J, Odamaki T, Kunisawa J, Mizuguchi K, Miyachi M (2021) Comprehensive analysis of gut microbiota of a healthy population and covariates affecting microbial variation in two large Japanese cohorts. BMC Microbiol 21: 151. PMID: 34016052. doi: 10.1186/s12866-021-02215-0.
Matsumoto N, Park J, Tomizawa R, Kawashima H, Hosomi K, Mizuguchi K, Honda C, Ozaki R, Iwatani Y, Watanabe M, Kunisawa J (2021) Relationship between nutrient intake and human gut microbiota in monozygotic twins. Medicina (Kaunas) 57(3): 275. PMID: 33809761. doi: 10.3390/medicina57030275.
Tabata T, Yamashita T, Hosomi K, Park J, Hayashi T, Yoshida N, Saito Y, Fukuzawa K, Konishi K, Murakami H, Kawashima H, Mizuguchi K, Miyachi M, Kunisawa J, Hirata K (2021) Gut microbial composition in patients with atrial fibrillation: effects of diet and drugs. Heart Vessels 36(1): 105-114. PMID: 32683492. doi: 10.1007/s00380-020-01669-y.
Tomizawa R, Park J, Hosomi K, Matsumoto N, Kawashima H, Mizuguchi K, Kunisawa J, Honda C (2021) Relationship between human gut microbiota and nutrition intake in hypertensive discordant monozygotic twins. J Hypertens (Los Angel) 10: 297.
大野治美, 村上晴香, 中潟崇, 谷澤薫平, 小西可奈, 宮地元彦 (2021) 習慣的な排便状況と便性状を評価する新しい質問票の再現性・内的妥当性の検討. 日本公衆衛生雑誌 68(2): 92-104. PMID: 33390507. doi: 10.11236/jph.20-037.
Chen YA, Park J, Natsume-Kitatani Y, Kawashima H, Mohsen A, Hosomi K, Tanisawa K, Ohno H, Konishi K, Murakami H, Miyachi M, Kunisawa J, Mizuguchi K (2020) MANTA, an integrative database and analysis platform that relates microbiome and phenotypic data. PLoS One 15(12): e0243609. PMID: 33275647. doi: 10.1371/journal.pone.0243609.
Watanabe D, Murakami H, Ohno H, Tanisawa K, Konishi K, Tsunematsu Y, Sato M, Miyoshi N, Wakabayashi K, Watanabe K, Miyachi M (2020) Association between dietary intake and the prevalence of tumourigenic bacteria in the gut microbiota of middle-aged Japanese adults. Sci Rep 10(1): 15221. PMID: 32939005. doi: 10.1038/s41598-020-72245-7.
Hosomi K, Kunisawa J (2020) Impact of the intestinal environment on the immune responses to vaccination. Vaccine 38(44): 6959-6965. PMID: 32933791. doi: 10.1016/j.vaccine.2020.08.079.
Sanada TJ, Hosomi K, Shoji H, Park J, Naito A, Ikubo Y, Yanagisawa A, Kobayashi T, Miwa H, Suda R, Sakao S, Mizuguchi K, Kunisawa J, Tanabe N, Tatsumi K (2020) Gut microbiota modification suppresses the development of pulmonary arterial hypertension in an SU5416/hypoxia rat model. Pulm Circ 10(3): 2045894020929147. PMID: 32922743. doi: 10.1177/2045894020929147.
Hosomi K, Kunisawa J (2020) Diversity of energy metabolism in immune responses regulated by micro-organisms and dietary nutrition. Int Immunol 32(7): 447-454. PMID: 32219308. doi: 10.1093/intimm/dxaa020.
Sato E, Hosomi K, Sekimoto A, Mishima E, Oe Y, Saigusa D, Ito S, Abe T, Sato H, Kunisawa J, Niwa T, Takahashi N (2020) Effects of the oral adsorbent AST-120 on fecal P-cresol and indole levels and on the gut microbiota composition. Biochem Biophys Res Commun 525(3): 773-779. PMID: 32147096. doi: 10.1016/j.bbrc.2020.02.141.
Hosomi K, Kiyono H, Kunisawa J (2020) Fatty acid metabolism in the host and commensal bacteria for the control of intestinal immune responses and diseases. Gut Microbes 11(3): 276-284. PMID: 31120334. doi: 10.1080/19490976.2019.1612662.
Mohsen A, Park J, Chen YA, Kawashima H, Mizuguchi K (2019) Impact of quality trimming on the efficiency of reads joining and diversity analysis of Illumina paired-end reads in the context of QIIME1 and QIIME2 microbiome analysis frameworks. BMC Bioinformatics 20(1): 581. PMID: 31730472. doi: 10.1186/s12859-019-3187-5.
Lan H, Hosomi K, Kunisawa J (2019) Clostridium perfringens enterotoxin-based protein engineering for the vaccine design and delivery system. Vaccine 37(42): 6232-6239. PMID: 31466706. doi: 10.1016/j.vaccine.2019.08.032.
Takahashi Y, Park J, Hosomi K, Yamada T, Kobayashi A, Yamaguchi Y, Iketani S, Kunisawa J, Mizuguchi K, Maeda N, Ohshima T (2019) Analysis of oral microbiota in Japanese oral cancer patients using 16S rRNA sequencing. J Oral Biosci 61(2): 120-128. PMID: 31109865. doi: 10.1016/j.job.2019.03.003.
Yoshii K, Hosomi K, Sawane K, Kunisawa J (2019) Metabolism of dietary and microbial vitamin B family in the regulation of host immunity. Front Nutr 6:48. PMID: 31058161. doi: 10.3389/fnut.2019.00048.
Ohno H, Murakami H, Tanisawa K, Konishi K, Miyachi M (2019) Validity of an observational assessment tool for multifaceted evaluation of faecal condition. Sci Rep 9(1): 3760. PMID: 30842504. doi: 10.1038/s41598-019-40178-5.
Hosomi, K, Ohno, H, Murakami, H, Natsume-Kitatani, Y, Tanisawa, K, Hirata, S, Suzuki, H, Nagatake, T, Nishino, T, Mizuguchi, K, Miyachi, M, Kunisawa, J (2017) Method for preparing DNA fromfeces in guanidine thiocyanate solution affects 16S rRNA-based profiling of human microbiota diversity. Sci Rep 7(1): 4339. PMID: 28659635. doi: 10.1038/s41598-017-04511-0.
Hosomi K, Kunisawa J (2017) The specific roles of vitamins in the regulation of immunosurveillance and maintenance of immunologic homeostasis in the gut. Immune Netw 17(1): 13-19. PMID: 28261016. doi: 10.4110/in.2017.17.1.13.